NAD+

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in all living cells, playing a central role in cellular energy metabolism, DNA repair, and gene expression regulation. It functions as a critical cofactor in redox reactions, shuttling electrons through the mitochondrial electron transport chain during cellular respiration.

Research interest in NAD+ has expanded substantially over the past two decades, driven by findings linking NAD+ depletion to aging phenotypes, metabolic dysfunction, and neurodegeneration. Preclinical and clinical studies have investigated NAD+ in the context of sirtuins (SIRT1–7), PARP enzymes, and CD38 activity — all NAD+-consuming pathways with significant implications for cellular health and longevity research.

Red Hand Research NAD+ is supplied as a lyophilized powder in 500mg and 1000mg options, independently verified to ≥99% purity by HPLC.